🦆 About PARIMA
PARIMA is Europe's leading cultivated foods company. We create sustainable cultivated meat delights directly from animal cells for a conscious generation. We believe in a world where succulence can share a table with a positive impact, and that cutting-edge technology combined with culinary arts can help us get there. From engineers and scientists to culinary experts, we're building an international team that shares the same passion for positive change. Currently a team of +40, we have dozens of nationalities at the table!
Check out Gourmey, our premium culinary brand!
🚀 Internship overview
Reporting directly to our Head of R&D, Remy Kusters, you will join a small, fast-moving R&D team working at the frontier of animal cell culture and protein production technology. We are developing a proprietary protein production platform for high-value proteins. Your work will directly shape whether this platform reaches its first commercial milestones.
Internship duration: 6 months
Location: Paris
🎯 Key responsibilities
60% Experimental — Protein Production & Optimization
- Cell processing & preparation: Help develop and refine our proprietary cell processing workflow, from culture harvest through downstream preparation steps.
- Production system optimisation: Run and optimise our protein production platform by systematically varying buffer composition, substrate supplementation strategies, redox conditions, and reaction parameters to maximise yield.
- Template engineering: Work with DNA constructs and reporter systems to benchmark expression output across conditions.
- DoE mindset: Help design and execute multi-variable optimization experiments; analyze results quantitatively and feed findings back into the next experimental cycle.
40% Analysis & Documentation
- Data pipelines: Process and visualize plate-reader, luminescence, and analytical data — Python preferred.
- Quantitative thinking: Contribute to kinetic interpretation of expression time-courses; work alongside a mechanistic ODE model of the reaction system.
- Protocol ownership: Maintain versioned, reproducible protocols and contribute to internal technical reports for the team and our research partners.
- Collaboration: Interface with our external research partner (a high-throughput automation platform) to help prepare joint experimental designs.
🔎 Who we're looking for
- Academic Background: You are currently enrolled in a final year Master's program in Biochemistry, Molecular Biology, Bioengineering, Chemical Biology, or a closely related field.
- Wet-lab skills: You are comfortable working independently in a molecular biology lab, cell culture and quantitative assay development are second nature to you.
- Protein expression experience: You have hands-on experience with at least one recombinant protein expression system (bacterial, yeast, mammalian, or insect). Curiosity about how different systems compare is a strong plus.
- Quantitative mindset: Experience with DoE, statistical analysis, or basic kinetic modeling is a genuine differentiator.
- Data fluency: You are comfortable processing and plotting experimental data in Python. You document your analyses so others can reproduce them.
- Ownership: You take pride in clean protocols, well-kept lab notebooks, and following an experiment through to a real conclusion.
- Mission-Driven: You are excited about applying cutting-edge biology to build something that matters. You thrive in a small team where your contribution is visible.
- Language: You are fluent in English. We are a very international team, no need to speak French!
📝 How to apply & hiring process
Send your Resume and a short paragraph explaining your motivation to remy@parima.bio
Process:
- Cultural fit: A first call to get to know each other.
- Short technical case study (to prepare at home).
