Scientist, Microbial Fermentation
Triplebar is on a mission to learn the language of biology using generative AI. We’re building cutting-edge models trained directly on millions of genomes, powered by the largest biological data engine on Earth. Our hyperthroughput platform evolves and screens biology at unprecedented scale, generating the data needed to teach machines how to design cells that can make anything.
We call this Evolutionary Intelligence: a new way to engineer biology, grounded in real data and aimed at solving the toughest problems in industrial biotech. Our first targets: protein production in microbial (Pichia pastoris) and mammalian (CHO) systems. Our goal: compress the timeline for designing an organism to produce any protein from years to seconds.
We’re looking for a driven, creative scientist to validate improved microbial strains at benchtop bioreactor scale. You’ll develop fermentation processes and methods to measure strain performance under industrially relevant conditions. Additionally you will provide inputs for scale down culture models and assay development.. You’ll collaborate with a tight-knit, world-class team spanning machine learning, bioinformatics, molecular biology, and microfluidics.
This is not just a job. It’s a chance to build something truly new, at the edge of what’s possible. If you want to go fast, dive deep, work hard, and make a dent in the universe, we want to meet you.
The role
As a full-time Scientist at Triplebar, you’ll own our fermentation screening function for all the microbial screening work we do. This is an opportunity to set up a Fermentation pipeline that collects relevant data at scale to power the next generation of AI models for strain engineering. You’ll take full ownership of the fermentation pipeline, from design through execution and analysis. Precision, creativity, and scientific rigor are all essential—you’ll have to challenge a lot of assumptions to run the fermentation function in a way that delivers on quality, throughput, and cost.
This is a hands-on, high-impact role at the cutting edge of synthetic biology, perfect for someone who’s ready to be part of building the future.
Your Contributions
Setup and run bench scale bioreactors. Analyze data collected from runs.
Work with ML/bioinformatics to incorporate data into data pipeline and re-enforcement learning strategy
Develop scalable fermentation processes for different organisms.
Channel your knowledge of fermentation conditions into the development of higher throughput small scale culture conditions.
Work with contractors, clients and CMOs.
Systematically test theories/hypotheses and drive conclusive results.
Take initiative to identify new areas for improvement and seek out new responsibilities to form a world class fermentation team.
Own results by making data-driven decisions, presenting results, and documenting findings.
Work closely with other parts of the org (assay development, build, ML/bioinformatics) to ensure the work fits into the larger Triplebar platform
Build company culture and serve as a role model for future hires
About you
Fermentation scientist with 3+ years of biotech/pharma experience.
Demonstrated experience in microbial fermentation at bench and pilot scale.
Deep expertise operating and scripting protocols on at least one bench-scale fermentation platform: DASGIP, AMBR, Bioflo or similar.
Strong knowledge of microbial physiology and cellular metabolism.
Highly-motivated self-starter that identifies issues and is intellectually curious to expand into new fields.
Willingness to self-evaluate, learn, and expand.
Enthusiastic about wearing many hats in a young and growing organization.
Builds and earns trust with coworkers to achieve team goals.
Based in Santa Monica-area, role will be on site
Not required, but exceptional candidates would also have...
Experience with advanced data analysis tools (e.g. Python, R, Matlab)
Experience with AI-assisted coding for workflow automation
Legal authorization to work in the U.S. is required. In compliance with federal law, all persons hired will be required to verify identity and eligibility to work in the United States and to complete the required employment eligibility verification form upon hire. This position is based in our Los Angeles, CA location.
